3`-Alkyne-Modifier Serinol CPG
Clickable Oligo Synthesis Building Block
- Catalog No.
- 100 mg
- € 210,00
- 1.0 g
- € 855,00
Our 3′-Alkyne-Modifier Serinol CPG is designed to introduce alkyne moieties efficently at the 3`end of oligos during standard solid phase synthesis. It can be used in a manner identical to normal (DMT-) protected nucleoside supports. The resulting oligo is then ready for click reactions with various azide moieties.
R. Kumar, A. El-Sagheer, J. Tumpane, P. Lincoln, L. M. Wilhelmsson, T. Brown, J. Am. Chem. Soc. 2007, 129, 6859–6864.
J. Lietard, A. Meyer, J. J. Vasseur, F. Morvan, Tetrahedron Lett. 2007, 48, 8795–8798.
12 months unopened after receipt
-20°C dry, inert gas
≥99% (Coupling Test)
white to off-white powder
3-Dimethoxytrityloxy-2-(3-(3-propargyloxypropanamido)-propanamido)propyl-1-O-succinoyl long chain alkylamino CPG
Coupling: This support should be used in a manner identical to normal protected nucleoside support since it contains the DMT group.
Deprotection: Room temperature Ammonium Hydroxide as required by nucleobases.
- Molecular Formula