We enable nucleic acid labeling bioconjugation
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Alkyne-ATP

Modified Triphosphate for chemo-enzymatic labeling of long oligonucleotides

Currency:  
  • Size
  • Catalog No.
  • Price
  • 0.5 µmol
  • BCT-22-S

  • € 90,00
  • 2.5 µmol
  • BCT-22-M

  • € 260,00
  • 5.0 µmol
  • BCT-22-L

  • € 400,00
Clear
  • The Alkyne-ATP can be incorporated into RNA using standard nucleotide mixtures and T7 RNA polymerase guided in-vitro transcription, or using a Poly-A Polymerase for 3`end labeling of your RNA sample. Ending up with a partially modified RNA (we recommend to replace the natural base by only 1-10% with the modified one), it is ready for labeling with our marker azides (e.g. fluorescent dyes for tracking and imaging or cross-linking to other biomolecules) by click chemistry.

    LITERATURE

    S.Croce, S. Serdjukow, T. Carell, T. Frischmuth, ChemBioChem, 2020, 21, 1-7

    • Molecular Formula

      C13H17N4O13P3

    • Shelf Life

      12 months unopened after receipt

    • Storage Conditions

      -20 °C

    • Molecular Weight

      530.22 g/mol

    • Purity

      ≥ 95% (NMR)

    • Physical State

      clear colorless to light brownish solution in water (100 mM)

    • CAS Number

      n.a.

    • Absorption (max)

      λmax = 278 nm

    • Additional name

      Alkyne-deoxyadenine-5’-triphosphate

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