Modified Triphosphate for chemo-enzymatic labeling of long oligonucleotides
- Catalog No.
- 0.5 µmol
- € 90,00
- 2.5 µmol
- € 260,00
- 5.0 µmol
- € 400,00
The Alkyne-ATP can be incorporated into RNA using standard nucleotide mixtures and T7 RNA polymerase guided in-vitro transcription, or using a Poly-A Polymerase for 3`end labeling of your RNA sample. Ending up with a partially modified RNA (we recommend to replace the natural base by only 1-10% with the modified one), it is ready for labeling with our marker azides (e.g. fluorescent dyes for tracking and imaging or cross-linking to other biomolecules) by click chemistry.
S.Croce, S. Serdjukow, T. Carell, T. Frischmuth, ChemBioChem, 2020, 21, 1-7
12 months unopened after receipt
≥ 95% (NMR)
clear colorless to light brownish solution in water (100 mM)
λmax = 278 nm
- Molecular Formula