We enable nucleic acid labeling bioconjugation
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Aminooxy-PEG3-Azide

Bifunctional PEG Linker

Currency:  
  • Size
  • Catalog No.
  • Price
  • 5.0 mg
  • BCL-034-5

  • € 85,00
  • 10 mg
  • BCL-034-10

  • € 130,00
Clear
  • The Aminooxy-PEG3-azide is a hetero-bifunctional reagent bearing an aminooxy group and an azide group. The azide allows to crosslink terminal-alkyne (bio-)molecules to compounds bearing aldehydes to generate an oxime bond. In presents of a reducing agent, it will form a hydroxylamine linkage. Thanks to the hydrophilic PEG spacer the compound is water soluble and thus treatment of biomolecules that treated in aqueous media is possible.

    LITERATURE

    G. N. Grover, J. Lee, N. M. Matsumoto, H. D. Maynardt, Macromolecules, 2012 Juni 26, 45(12), 4858-4965

    N. Boehnke, C. Cam, E. Bat, T. Segura, H- D. Maynardt, Biomacromolecules, 2015 Jul 13, 16(7), 2101-8

    P. Carberry, A. P. Carpenter, H. F. Kung, Bioorg Med. Chem. Lett., 2011 Dec 1, 21(23), 6992-5

    R.J. Mancini, S.J. Paluck, E. Bat, H. D. Maynardt, Langmuir, 2016 Apr 26, 32(16), 4043-51

    Y. Jin, L. Song, Y. Su, L. Zhu, Y. Pang, F. Qiu, G. Tong, D. Yan, B. Zhu, X. Zhu, Biomacromolecules, 2011 Oct 10, 12(10), 3460-8

    M. Rashidian, S. C. Kumarapperuma, K. Gabrielse, A. Fegan, C. R. Wagner, M. D. Distefano, J. Am. Chem. Soc., 2013 Nov 6, 135(44), 16388-96

    J. G. Hardy, P. Jin, C. E. Schmidt, J Biomater Sci Polym Ed., 2015, 26(3):14, 3-61.

    • Molecular Formula

      C8H18N4O4

    • Shelf Life

      12 months unopened after receipt

    • Storage Conditions

      2-8 °C

    • Molecular Weight

      234.25 g/mol

    • Purity

      ≥ 90 % (TLC)

    • Physical State

      pale yellow oil

    • CAS Number

      1306615-51-9

    • Solubility

      DMSO, DMAC, DCM, ACN

    • Preparation/Handling

      For a 10 mM solution add 426 μL to 1mg.

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