We enable nucleic acid labeling bioconjugation
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C8-Alkyne-dA CEP

Clickable Oligo Synthesis Building Block

Currency:  
  • Size
  • Catalog No.
  • Price
  • 50 µmol (46.36 mg)
  • BCA-27-50

  • € 300,00
  • 100 µmol (92.71 mg)
  • BCA-27-100

  • € 560,00
  • 250 mg
  • BCA-27-250

  • € 1.200,00
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  • This special DNA phosphoramidite with a C8-Spacer between the reactive alkyne group and the backbone is used under standard conditions for solid phase synthesis of oligonucleotides. It has shown to be incorporated into DNA oligomers with excellent coupling efficiency and subsequent use of those oligonucleotides in click reactions is achieved using our different azide labels.

    LITERATURE

    F. Seela, V. R. Sirivolu, P. Chittepu, Bioconjug. Chem. 2008, 19, 211–224.

    • Molecular Formula

      C53H63N6O7P

    • Shelf Life

      12 months unopened after receipt

    • Storage Conditions

      dry, -20°C

    • Molecular Weight

      927.10 g/mol

    • Purity

      ≥ 95% (TLC & 31P-NMR)

    • Physical State

      white to off-white foam

    • CAS Number

      n.a.

    • Preparation/Handling

      Solid-Phase Synthesis Information:
      Diluent: Anhydrous acetonitrile (0.1 M final concentration is recommended)
      Coupling: Standard protocol as recommended by synthesizer manufacturer.
      Deprotection: Standard protocol as for oligonucleotides from standard phosphoramidites.