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C8-Alkyne-dA CEP
Clickable Oligo Synthesis Building Block
- Size
- Catalog No.
- Price
- 50 µmol (46.36 mg)
BCA-27-50
- € 300,00
- 100 µmol (92.71 mg)
BCA-27-100
- € 560,00
- 250 mg
BCA-27-250
- € 1.200,00
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This special DNA phosphoramidite with a C8-Spacer between the reactive alkyne group and the backbone is used under standard conditions for solid phase synthesis of oligonucleotides. It has shown to be incorporated into DNA oligomers with excellent coupling efficiency and subsequent use of those oligonucleotides in click reactions is achieved using our different azide labels.
LITERATURE
F. Seela, V. R. Sirivolu, P. Chittepu, Bioconjug. Chem. 2008, 19, 211–224.
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Molecular Formula
C53H63N6O7P
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Shelf Life
12 months unopened after receipt
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Storage Conditions
dry, -20°C
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Molecular Weight
927.10 g/mol
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Purity
≥ 95% (TLC & 31P-NMR)
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Physical State
white to off-white foam
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CAS Number
n.a.
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Preparation/Handling
Solid-Phase Synthesis Information:
Diluent: Anhydrous acetonitrile (0.1 M final concentration is recommended)
Coupling: Standard protocol as recommended by synthesizer manufacturer.
Deprotection: Standard protocol as for oligonucleotides from standard phosphoramidites.
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Molecular Formula