We enable nucleic acid labeling bioconjugation
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C8-Alkyne-dC-CEP

Clickable Oligo Synthesis Building Block

Currency:  
  • Size
  • Catalog No.
  • Price
  • 250 mg
  • BCA-07-250

  • € 240,00
  • 1.0 g
  • BCA-07-1g

  • € 780,00
  • 5.0 g
  • BCA-07-5g

  • € 3.700,00
Clear
  • This special DNA phosphoramidite with a C8-Spacer between the reactive alkyne group and the backbone is used under standard conditions for solid phase synthesis of oligonucleotides. It has shown to be incorporated into DNA oligomers with excellent coupling efficiency and subsequent use of those oligonucleotides in click reactions is achieved using our different azide labels.

    LITERATURE

    P. M. E. Gramlich, S. Warncke, J. Gierlich, T. Carell, Angew. Chemie – Int. Ed. 2008, 47, 3442–3444.

    P. M. E. Gramlich, C. T. Wirges, A. Manetto, T. Carell, Angew. Chemie – Int. Ed. 2008, 47, 8350–8358.

    • Molecular Formula

      C54H60N5O8P

    • Shelf Life

      12 months unopened after receipt

    • Storage Conditions

      -20°C dry, inert gas

    • Molecular Weight

      938.06 g/mol

    • Purity

      ≥95% (31P(III) NMR)

    • Physical State

      white to off-white solid

    • CAS Number

      n.a.

    • Additional name

      4-N-Benzoyl-5-(octa-1,7-diynyl)-3´-O-[(2-cyanoethoxy)(diisopropylamino)-phosphono)]-5´-O-(4,4´-dimethoxytrityl)-2’-deoxycytidine

    • Preparation/Handling

      This phosphoramidite is used under standard conditions for solid phase synthesis of oligonucleotides.

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