Product Application for...
Product Emission color
Product Enatiomeric structure
Product Kits for..
Product Label Position
Product Linker type
Product Modification Type
Product Nucleoside
Product Nucleosites
Product Protection Type
Product Sort by
Product Sugar core
C8-Alkyne-dU-CEP
Clickable Oligo Synthesis Building Block
- Size
- Catalog No.
- Price
- 250 mg
BCA-03-250
- € 210,00
- 1.0 g
BCA-03-1g
- € 630,00
- 5.0 g
BCA-03-5g
- € 2.500,00
-
This special DNA phosphoramidite with a C8-Spacer between the reactive alkyne group and the backbone is used under standard conditions for solid phase synthesis of oligonucleotides. It has shown to be incorporated into DNA oligomers with excellent coupling efficiency and subsequent use of those oligonucleotides in click reactions is achieved using our different azide labels.
LITERATURE
F. Seela, V. R. Sirivolu, Nucleosides, nucleotides {&} nucleic acids 2007, 26, 597–601.
D. M. M. Hammond, A. Manetto, J. Gierlich, V. A. A. Azov, P. M. E. M. E. Gramlich, G. A. A. Burley, M. Maul, T. Carell, Angew. Chem. 2007, 119, 4262–4265.
D. I. Rozkiewicz, J. Gierlich, G. A. Burley, K. Gutsmiedl, T. Carell, B. J. Ravoo, D. N. Reinhoudt, ChemBioChem 2007, 8, 1997–2002.
F. Seela, V. R. Sirivolu, Chem. Biodivers. 2006, 3, 509–514.
J. Gierlich, G. a. Burley, P. M. E. Gramlich, D. M. Hammond, T. Carell, Org. Lett. 2006, 8, 3639–3642.
-
-
Molecular Formula
C47H55N4O8P
-
Shelf Life
12 months unopened after receipt
-
Storage Conditions
-20 °C dry, inert gas
-
Molecular Weight
834.94 g/mol
-
Purity
≥ 95% (HPLC & 31P-NMR)
-
Physical State
white to off-white / light yellow solid
-
CAS Number
938186-76-6
-
Additional name
5-(Octa-1,7-diynyl)-3`-O-[(2-cyanoethoxy)(diisopropylamino)-phosphono)]-5`-O- (4,4`-dimethoxytrityl)-2`-deoxyuridine
-
Preparation/Handling
C8-Alkyne-dU-CEP is used under standard conditions for solid phase synthesis of oligonucleotides.
-
Molecular Formula