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C8-TIPS-dC-CEP
Clickable Oligo Synthesis Building Block

- Size
- Catalog No.
- Price
- 250 mg
BCA-08-250
- € 105,00
- 1.0 g
BCA-08-1g
- € 340,00
- 5.0 g
BCA-08-5g
- € 1.600,00
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This phosphoramidite is used under standard conditions for solid phase synthesis of oligonucleotides. It has shown to be incorporated into DNA oligomers with good coupling efficiency. The protection group on the alkyne can be exploited to introduce different labels by click chemistry into one oligo. Having reacted a first group and purified the compound, the TIPS can then be deprotected and is thus ready for a second click reaction with another click azide on the same product.
LITERATURE
P. M. E. Gramlich, S. Warncke, J. Gierlich, T. Carell, Angew. Chemie – Int. Ed. 2008, 47, 3442–3444.
P. M. E. Gramlich, C. T. Wirges, A. Manetto, T. Carell, Angew. Chemie – Int. Ed. 2008, 47, 8350–8358.
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Molecular Formula
C63H80N5O8PSi
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Shelf Life
12 months unopened after receipt
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Storage Conditions
-20°C dry, inert gas
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Molecular Weight
1094.4 g/mol
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Purity
≥ 95 %(HPLC)
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Physical State
white to off-white solid
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CAS Number
n.a.
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Additional name
TIPS-5-Ethynyl dU CEP; TIPS-5-Ethynyl dU Phosphoramidite
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Preparation/Handling
This phosphoramidite is used under standard conditions for solid phase synthesis of oligonucleotides.
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Molecular Formula