Bifunctional PEG Linker
- Catalog No.
- 5.0 mg
- € 55,00
- 10 mg
- € 80,00
This hetero-bifunctional reagent allows to crosslink alkyne (bio-)molecules to compounds bearing primary amines. The NHS ester group will react covalently with primary amines while the azide can undergo click reaction in catalyzed conditions with terminal alkynes. Thanks to the hydrophilic PEG spacer the compound is water soluble and thus treatment of biomolecules that treated in aqueous media is possible.
H. C. Kolb, B. Sharpless, K. B. Sharpless, Drug Discov. Today 2003, 8, 1128–1137.
H. C. Kolb, M. G. Finn, K. B. Sharpless, Angew. Chemie – Int. Ed. 2001, 40, 2004–2021.
V. D. Bock, H. Hiemstra, J. H. Van Maarseveen, European J. Org. Chem. 2006, 51–68.
12 months unopened after receipt
-20 °C, dry, inert gas
≥ 90% (HPLC)
colourless to yellow liquid
N3-dPEG(12)-NHS; 1-Azido-3,6,9,12,15,18,21,24,27,30,33,36-dodecaoxanonatriacontan-39-oic acid succinimidyl ester
DCM, DMAC, DMSO, ACN
For a 10 mM solution add 134 μL to 1mg.
- Molecular Formula