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mRNA Configurator

Welcome to our mRNA Configurator section!

Click technology holds the promise to revolutionize the mRNA Technology in drug development for cancer treatment, vaccine discovery and enables tailored manufactured mRNA with superior quality.

Since 2022, baseclick is guiding provider in custom messenger in vitro mRNA synthesis and modification for research and clinical applications. Our team of experts transforms your mRNA design ranging from research tool to mRNA product development.

baseclick supplies diverse types of mRNA

  • High quality products and services at competitive prices
  • Custom tailored support to meet specific applications
  • Wide variety of modification
  • Affordable custom synthesis up to 10 mg scales of mRNA

LITERATURE

Chemoenzymatic Preparation of Functional Click-Labeled Messenger RNA, S. Croce et al., 2020, ChemBioChem, Vol. 21, p. 1641.

https://doi.org/10.1002/cbic.201900718

5-Ethynyluridine: a bio-orthogonal uridine variant for mRNA-based therapies and vaccines, S. Maassen et al., 2023, ChemBioChem, Vol. 24, p. e202200658.

https://doi.org/10.1002/cbic.202200658

 

We offer different modifications of mRNA.

modifications of mRNA

Template Source

To proceed with your request, it is required that your template contains a T7 promoter site. Please provide the sequence of the three bases immediately after the T7 promoter:

ARCA Cap Analog requires the initiation sequence 5’ GG 3’

Purity by A260/A280 ratio and Integrity by denaturing Agarose Gel

Incorporation quality control (5'end / 3'end)

Template Source

To proceed with your request, it is required that your template contains a T7 promoter site. Please provide the sequence of the three bases immediately after the T7 promoter:

CleanCap AG requires the initiation sequence 5’ AGG 3’ ARCA Cap Analog requires the initiation sequence 5’ GG 3’

Purity by A260/A280 ratio and Integrity by denaturing Agarose Gel

Incorporation quality control (5'end / 3'end)

Template Source

To proceed with your request, it is required that your template contains a T7 promoter site. Please provide the sequence of the three bases immediately after the T7 promoter:

CleanCap AG requires the initiation sequence 5’ AGG 3’ ARCA Cap Analog requires the initiation sequence 5’ GG 3’

Purity by A260/A280 ratio and Integrity by denaturing Agarose Gel

Incorporation quality control (5'end / 3'end)