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Triphosphate for cap modifying of 5'END RNA

Size Catalog No. Price
1 µmol BCT-32-S 800 €
  • 3′-(O-Propargyl)-GTP can be incorporated in RNA at the 3’end using poly(A) Polymerase. But for adding an alkyne to the 3′-end 3′-(O-Propargyl)-ATP (BCT-31) is superior. We developed a different approach in which 3′-(O-Propargyl)-GTP is added to mRNA to the 5’end with an capping enzyme and afterwards methylated. As a result a cap-like structure is created which provides all the advantages of a cap structure together with the possibility to perform click reactions at the incorporated alkyne.

    • Molecular Formula

      C13H18N5O14P3 (free acid)

    • Shelf Life

      12 months unopened after receipt

    • Storage Conditions

      -20 °C, dark, dry

    • Molecular Weight

      561.23 g/mol (free acid)

    • Purity

      ≥ 95% (HPLC)

    • Physical State

      colorless to white solid

    • CAS Number


    • Absorption (max)

      λmax = 252 nm

    • Ɛ (max)

      13.700 cm-1M-1

    • Salt Form

      Triethylammonium salt