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7-Ethynyl-dA-CE Phosphoramidite
Clickable phosphoramidite for Oligo synthesis
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With 7-Ethynyl-dA-CE Phosphoramidite it is possible to introduce alkyne modified A in the oligonucleotide. After standard solid phase synthesis, the final oligo is ready for subsequent click reaction.
LITERATURE
Rational design, synthesis, and photophysics of dual-emissive deoxyadenosine analogs, H. N. Le et al., 2019, Dyes and Pigments, Vol. 170, p. 107553.
https://doi.org/10.1016/j.dyepig.2019.107553
Nucleotides and nucleic acids; oligo-and poly-nucleotides, D. Loakes, 2014, In Organophosphorus Chemistry, p. 146-245.
(no link available)
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Molecular Formula
C47H55N6O7P
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Shelf Life
12 months unopened after receipt
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Storage Conditions
-20 °C, dry, inert gas
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Molecular Weight
846.95 g/mol
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Purity
≥ 90% (HPLC and 31P NMR)
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Physical State
white to off-white, solid
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CAS Number
1269636-33-0
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Molecular Formula