DBCO-C6-Alkyne
Bifunctional linker

- Size
- Catalog No.
- Price
- 5 mg
BCL-035-5
- € 80,00
- 10 mg
BCL-035-10
- € 130,00
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The heterobifunctional linker DBCO-C6-Alkyne contains an Alkyne and a DBCO moiety which enable the possibility to perform two sequential click reactions in an orthogonal way. Therefore this linker offers a great potential to cross link to azide containg biomolecules by just using high efficient Click Chemistry. There is also the possibility to selectively click the alkyne before the DBCO [1]. Therefore this linker offers great potential for the synthesis of Antibody-drug-conjugates (ADC).
LITERATURE
[1] Transient protection of strained alkynes from click reaction via complexation with copper, S. Yoshida et al., 2014, Journal of the American Chemical Society, Vol. 136(39), p. 13590-13593.
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- Molecular Formula
C24H22N2O2
- Shelf Life
12 months unopened after receipt
- Storage Conditions
-20 °C, dark
- Molecular Weight
370.45 g/mol
- Purity
≥ 95% (HPLC)
- Physical State
slightly grey solid
- CAS Number
n.a.
- Additional name
N-(propargylamidoadipoyl)-dibenzoazacyclooctyne
- Solubility
DMSO, DMF, DCM, THF, Chloroform
- Preparation/Handling
For a 10 mM solution add 1350 μL to 5 mg.
For a 10 mM solution add 2699 μL to 10 mg.
- Molecular Formula