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Azido-hexynyl-pApG
Initiator for increasing IVT of RNA
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Azido-hexynyl-pApG works as an initiator for mRNA translation and provides similar enhancement in stability and activity as capping reagents. The introduced azide function operates also as an reporter by modifiying the enzymatic capped mRNA via Click Chemistry either via SPAAC or by CuAAC. Since most RNAs are partially degraded by Cu(I) baseclick recommends labeling in copper free via SPAAC for example with our DBCO dyes.
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Molecular Formula
C26H37N13O14P2 (free acid)
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Shelf Life
12 months unopened after receipt
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Storage Conditions
-20 °C, dark, dry
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Molecular Weight
817.60 g/mol (free acid)
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Purity
≥ 95% (HPLC)
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Physical State
colorless solution (10 mM)
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CAS Number
n.a.
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Absorption (max)
λmax = 256 nm
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Ɛ (max)
25.050 cm-1M-1
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Molecular Formula