We enable nucleic acid labeling bioconjugation
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Clean Cap

Cap structure for increasing IVT yield of RNA

  • Size
  • Catalog No.
  • Price
  • 1 µmol
  • BCT-38-S

  • 350 €
  • Clean Cap modified mRNA exhibits a longer half-life and the translation efficiency is increased by using this cap analog during in vitro transcription for the generation of capped transcripts.



    Chemical modifications of adenine base editor mRNA and guide RNA expand its application scope, T. Jiang et al., 2020, Nature Communications, Vol. 11, 1979.


    Cap 1 messenger RNA synthesis with co‐transcriptional cleancap® analog by in vitro transcription, J. M. Henderson et al., 2021, Current Protocols, Vol. 1(2), e39.


    • Molecular Formula

      C32H43N15O24P4 (free acid)

    • Shelf Life

      12 months unopened after receipt

    • Storage Conditions

      -20 °C, dark, dry

    • Molecular Weight

      1145.60 g/mol (free acid)

    • Purity

      ≥ 95% (HPLC)

    • Physical State

      colorless solution (100 mM)

    • CAS Number


    • Absorption (max)

      λmax = 255 nm

    • Ɛ (max)

      30.539 cm-1M-1

    • Additional name


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