EdU

EdU (5-ethynyl-2’-deoxyuridine) is a nucleoside analog to thymidine and can be incorporated into DNA during active DNA synthesis (see also our EdU cell proliferation assays for more information). The resulting DNA carries alkyne handles that can be easily conjugated to label-azides for convenient fluorescent read-outs to assess cell proliferation, cell cycles, viability, etc.

LITERATURE

R. Kumar, A. El-Sagheer, J. Tumpane, P. Lincoln, L. M. Wilhelmsson, T. Brown, J. Am. Chem. Soc. 2007, 129, 6859–6864.

V. V. Rostovtsev, L. G. Green, V. V. Fokin, K. B. Sharpless, Angew. Chemie – Int. Ed. 2002, 41, 2596–2599.