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Dye to label by SPAAC in copper-free environment

Size Catalog No. Price
1 mg BCFA-237-1 € 200,00
5 mg BCFA-237-5 € 650,00
  • This green-fluorescent DBCO-AF488 dye enables the possibility for copper-free click chemistry which is mostly used in reaction where cytotoxic copper catalyst is not an option. The click reaction takes place via strain-promoted Alkyne-Azide Chemistry (SPAAC) which does not need a Cu (I) catalysis or heating. Once clicked to a biomolecule fluorescence detection is identical to FAM, FITC, or any other alternative dye.



    A metabolic labeling way to in situ fabricate bacterial FRET Platform for innate immune defence molecule, Z. Zhang et al., 2022, Sensors and Actuators B: Chemical, Vol. 350, 130913.


    Model of collective detachment in high-grade serous ovarian cancer demonstrates that tumor spheroids produce ECM to support metastatic processes, H. M. Micek et al., 2023, APL Bioengineering, Vol. 7(1), 016111.


    Investigating Peptidoglycan Recycling Pathways in Tannerella forsythia with N-Acetylmuramic Acid Bioorthogonal Probes, K. A. Wodzanowski et al., 2022, ACS Infect. Dis., Vol. 8(9), p. 1831–1838.


    • Molecular Formula


    • Shelf Life

      12 months unopened after receipt

    • Storage Conditions

      -20 °C, dark

    • Molecular Weight

      792.8 g/mol

    • Purity

      ≥ 95% (HPLC)

    • Physical State

      orange solid

    • CAS Number


    • Excitation (max)

      495 nm

    • Emission (max)

      517 nm

    • Ɛ (max)

      73.000 cm-1M-1

    • Solubility

      H2O, DMSO, DMF

    • Preparation/Handling

      For a 10 mM solution add 126 μL to 1 mg.
      For a 10 mM solution add 631 μL to 5 mg.