• filter
Currency:  
[woof sid="shoppingCart" autohide=0]

Tri-β-GalNAc-PEG3-Azide

Clickable Tri-GalNAc identifier for target delivery

Size Catalog No. Price
5 mg BCFA-246-5 € 450,00
10 mg BCFA-246-10 € 760,00
Clear
  • Tri-β-GalNAc-PEG3-Azide enables the possibility to click label an Alkyne or DBCO modified target with an Tri-GalNAc moiety by copper-catalyzed Azide-Alkyne Chemistry (CuAAC). The Tri-GalNAc structure is recognized by the desialic acid glycoprotein receptor (ASGPR) and can be therefore used to target delivery of biomolecules as siRNA to liver tissue.

     

    LITERATURE

    Probing multivalent carbohydrate-protein interactions with on-chip synthesized glycopeptides using different functionalized surfaces, A. Tsouka et al., 2021, Frontiers in Chemistry, Vol. 9, 766932.

    https://doi.org/10.3389/fchem.2021.766932

    • Molecular Formula

      C70H125N13O31

    • Shelf Life

      12 months unopened after receipt

    • Storage Conditions

      -20 °C, dark

    • Molecular Weight

      1644.8 g/mol

    • Purity

      ≥ 95% (HPLC)

    • Physical State

      white solid

    • CAS Number

      n.a.

    • Additional name

      Tri-β-GalNAc-PEG3-N3, (β-D-GalNAc)3-PEG3-N3, (β-D-GalNAc-sp)3-NHC(O)-PEG3-N3

    • Solubility

      H2O, DMSO

    • Preparation/Handling

      For a 10 mM solution add 304 μL to 5 mg.
      For a 10 mM solution add 608 μL to 10 mg.

X