5-Carboxytetramethylrhodamine-PEG3-Azide (5-TAMRA-PEG3-Azide)
Fluorescent dye to label DNA/RNA
| Size | Catalog No. | Price |
|---|---|---|
| 5 mg | BCFA-037-5 | € 80,00 |
| 10 mg | BCFA-037-10 | € 125,00 |
| 100 mg | BCFA-037-100 | € 500,00 |
Chemical Properties
-
Molecular Formula
C33H38N6O7
-
Shelf Life
12 months unopened after receipt
-
Storage Conditions
-20 °C, dark
-
Molecular Weight
630.69 g/mol
-
Purity
≥ 90% (HPLC)
-
Physical State
pink to dark red solid
-
CAS Number
1380486-02-1
-
Additional name
5-Carboxytetramethylrhodamine-PEG3-Azide
-
Excitation (max)
DMF or DMSO: 546 nm
-
Emission (max)
DMF or DMSO: 579 nm
-
Ɛ (max)
91,000 cm-1M-1
-
Solubility
DMSO, DMF, MeOH, slightly soluble in water
-
Preparation/Handling
For a 10 mM solution add 158 μL to 1 mg.
Product Information
5-Carboxytetramethylrhodamine-PEG3-Azide (5-TAMRA-PEG3-Azide) has the same properties as 5-TAMRA-azide, but has a PEG3 spacer that separates the dye core from the attachable biomolecule and thus minimizes possible interactions between both.
LITERATURE
Postsynthetic DNA Modification through the Copper-Catalyzed Azide–Alkyne Cycloaddition Reaction, P. M. E. Gramlich et al., 2008, Angew. Chemie Int. Ed., Vol. 47, p. 8350–8358.
https://doi.org/10.1002/anie.200802077
Click–Click–Click: Single to Triple Modification of DNA, P. M. E. Gramlich et al., 2008, Angew. Chemie Int. Ed., Vol. 47, p. 3442-3444.
https://doi.org/10.1002/anie.200705664
A chemical method for fast and sensitive detection of DNA synthesis in vivo, A. Salic et al., 2008, Proc. Natl. Acad. Sci. U. S. A., Vol. 105, p. 2415–2420.
https://doi.org/10.1073/pnas.0712168105
Chemoenzymatic Preparation of Functional Click-Labeled Messenger RNA, S. Croce et al., 2020, ChemBioChem, Vol. 21(11), p. 1641-1646.
https://doi.org/10.1002/cbic.201900718
Synthesis and biological evaluation of anthracene-9,10 dione derivatives as CK2 inhibitors, P. López-Rojas et al., 2023, Results in Chemistry, Vol. 6, p. 100997.