5-Carboxytetramethylrhodamine-PEG3-Azide (5-TAMRA-PEG3-Azide)

5-Carboxytetramethylrhodamine-PEG3-Azide (5-TAMRA-PEG3-Azide) has the same properties as 5-TAMRA-azide, but has a PEG3 spacer that separates the dye core from the attachable biomolecule and thus minimizes possible interactions between both.

LITERATURE

Postsynthetic DNA Modification through the Copper-Catalyzed Azide–Alkyne Cycloaddition Reaction, P. M. E. Gramlich et al., 2008, Angew. Chemie Int. Ed., Vol. 47, p. 8350–8358.

https://doi.org/10.1002/anie.200802077

Click–Click–Click: Single to Triple Modification of DNA, P. M. E. Gramlich et al., 2008, Angew. Chemie Int. Ed., Vol. 47, p. 3442-3444.

https://doi.org/10.1002/anie.200705664

A chemical method for fast and sensitive detection of DNA synthesis in vivo, A. Salic et al., 2008, Proc. Natl. Acad. Sci. U. S. A., Vol. 105, p. 2415–2420.

https://doi.org/10.1073/pnas.0712168105

Chemoenzymatic Preparation of Functional Click-Labeled Messenger RNA, S. Croce et al., 2020, ChemBioChem, Vol. 21(11), p. 1641-1646.

https://doi.org/10.1002/cbic.201900718

Synthesis and biological evaluation of anthracene-9,10 dione derivatives as CK2 inhibitors, P. López-Rojas et al., 2023, Results in Chemistry, Vol. 6, p. 100997.

https://doi.org/10.1016/j.rechem.2023.100997