Na-Ascorbate
"baseclick-grade" reducing agent for optimal click reaction
| Size | Catalog No. | Price |
|---|---|---|
| 5 x 10 mg | BCMI-005-10×5 | € 45,00 |
| 10 x 10 mg | BCMI-005-10×10 | € 75,00 |
Chemical Properties
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Molecular Formula
C6H7NaO6
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Shelf Life
12 months unopened after receipt
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Storage Conditions
2-8 °C, store dry
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Molecular Weight
198.11 g/mol
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Purity
≥ 99% (iodometric)
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Physical State
white to slightly yellow crystals
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CAS Number
134-03-2
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Additional name
Sodium Ascorbate
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Solubility
aqueous solution
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Preparation/Handling
Used as reducing agent for Copper(II) sulfate (CuSO4) to perform click reactions in aqueous media
Product Information
The water-soluble CuSO4 reagent is for performing click reactions in aqueous solution e.g. for experiments with cell culture or sensitive biomolecules that do not tolerate DMSO. In order to create the click reactive Cu(I) species, Na-Ascorbate is needed to reduce Cu(II). Additionally, please make sure using a water-soluble ligand (e.g. THPTA) protecting your biomolecule.
LITERATURE
Functionalization of the surface of electrospun poly(epsilon-caprolactone) mats using zwitterionic poly(carboxybetaine methacrylate) and cell-specific peptide for endothelial progenitor cells capture, Q. Li et al., 2013, Mater. Sci. Eng., Vol. 33(3), p. 1646-1653.
https://doi.org/10.1016/j.msec.2012.12.074
Synthesis of in situ functionalized iron oxide nanoparticles presenting alkyne groups via a continuous process using near-critical and supercritical water, M. D. de Tercero, 2013, J Supercrit Fluids, Vol. 82, p. 83-95.