Tri-β-GalNAc-PEG3-Azide
Clickable Tri-GalNAc identifier for target delivery
| Size | Catalog No. | Price |
|---|---|---|
| 5 mg | BCFA-246-5 | € 450,00 |
| 10 mg | BCFA-246-10 | € 760,00 |
Chemical Properties
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Molecular Formula
C70H125N13O31
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Shelf Life
12 months unopened after receipt
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Storage Conditions
-20 °C, dark
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Molecular Weight
1644.8 g/mol
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Purity
≥ 95% (HPLC)
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Physical State
white solid
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CAS Number
n.a.
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Additional name
Tri-β-GalNAc-PEG3-N3, (β-D-GalNAc)3-PEG3-N3, (β-D-GalNAc-sp)3-NHC(O)-PEG3-N3
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Solubility
H2O, DMSO
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Preparation/Handling
For a 10 mM solution add 304 μL to 5 mg.
For a 10 mM solution add 608 μL to 10 mg.
Product Information
Tri-β-GalNAc-PEG3-Azide enables the possibility to click label an Alkyne or DBCO modified target with an Tri-GalNAc moiety by copper-catalyzed Azide-Alkyne Chemistry (CuAAC). The Tri-GalNAc structure is recognized by the desialic acid glycoprotein receptor (ASGPR) and can be therefore used to target delivery of biomolecules as siRNA to liver tissue.
LITERATURE
Probing multivalent carbohydrate-protein interactions with on-chip synthesized glycopeptides using different functionalized surfaces, A. Tsouka et al., 2021, Frontiers in Chemistry, Vol. 9, 766932.